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FacultyLeah Seebald

Leah Seebald
Leah Seebald
she/her
Assistant Professor of Chemistry
370 Lancaster Ave
lseebald [at] haverford.edu
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Publications

My background and current work is broadly interested in the development of new chemical tools to support biological research. I did my PhD at SUNY Albany under the advisement of Dr. Maksim Royzen designing and synthesizing paramagnetic NMR probes appended to RNA for enabling solution state RNA-protein structural studies. My postdoctoral work was carried out with Dr. Barbara Imperiali at MIT where I synthesized covalent probes for targeting enzymes responsible for the membrane initiation of bacterial glycosylation products. My current research leverages organic synthesis and rational chemical design to create new biological probes (bio-probes) that enable selective targeting of biological macromolecules from complex cellular environments. In particular, I am interested in generating libraries of compounds comprising electrophilic moieties through diversity-oriented synthesis. I am also interested in investigating new synthetic strategies for making complex bacterial sugars.

Here is my lab website for more information

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