This project attempts to present some of the basics of organic chemistry in video lectures. The goal is to provide a talking textbook. Each lecture is divided into short segments for easy reference. The videos, as well as related text, are intended for any student who is interested in learning organic chemistry.
Lecture 1 -Introduction
Lecture 2 - Conformation
Lecture 3 - Constitution
Lecture 4 - ConfigurationLoading the player...
Lecture 5 - Hydrocarbon Rings
Lecture 6 - StereotopismLoading the player...
- 6.01 Constitutionally Distinguishable Groups related text
- 6.02 Homotopic Groups related text
- 6.03 Enantiotopic Groups related text
- 6.04 Diastereotopic Groups related text
- 6.05 Stereotopism in 3,5-Dimethyl heptane related text
- 6.06 Re and Si Faces and Spaces related text
- 6.07 Stereotopism in Ethanol related text
Lecture 7 - Carbon BondingLoading the player...
- 7.01 Hydrogen Molecule related text, related text: addendum)
- 7.02 Csp3 Bonding - Methane related text
- 7.03 Csp2 Bonding - Ethylene related text
- 7.04 Csp2 Bonding - Ethylene, continued related text
- 7.05 Csp Bonding - Acetylene related text
- 7.06 Allene (1,2-Propadiene) related text
- 7.07 Tau Bonds ("Bent Bonds") related text
- 7.08 E/Z Nomenclature related text
Lecture 8 - Bonding in Carbon Polyene SystemsLoading the player...
Lecture 9 - Basic Ideas of Thermodynamics and Kinetics
Lecture 10 - FunctionalityLoading the player...
- 10.01 The Concepts Primary, Secondary, Tertiary related text
Lecture 11 - Acidity and BasicityLoading the player...
- 11.01 Aqueous Acids and Bases - pKA related text
- 11.02 The Lewis Nucleophile-Electrophile Definition related text
- 11.03 Avoiding Error When Invoking Aqueous Acids and Bases related text
- 11.04 Potential Delocalization of an Anion Affects Acidity related text
- 11.05 Kinetic vs. Thermodynamic (Equilibrium) Acidity related text
- 11.06 Nucleophilicity vs. Basicity related text
Lecture 12 - Oxidation and Reduction: Forms of Writing ReactionsLoading the player...
- 12.01 Balancing Redox Reactions related text
- 12.02 Reduction of Alkenes - Forms of Writing Reactions related text
- 12.03 Oxidation of Alkenes to Oxiranes (Epoxides) related text
- 12.04 Oxidation of Alkenes to 1,2-Diols (Cis-Oxidation) related text
- 12.05 Diastereoselectivity in Redox Reactions related text
- 12.06 Enantioselectivity in Redox Reactions related text
Lecture 13 - Bimolecular Nucleophilic Substitution and Elimination ReactionsLoading the player...
- 13.01 Bimolecular Nucleophilic Substitution related text
- 13.02 The SN2 Mechanism related text
- 13.03 The Special Case of Primary Halide Synthesis related text
- 13.04 Steric Effects on the SN2 Mechanism related text
- 13.05 The E2 Mechanism Competes with SN2 related text
- 13.06 Stereochemistry of the E2 Reaction related text
- 13.07 Synthesis of Isopropyl Methyl Ether related text
Lecture 14 - Unimolecular Nucleophilic Substitution and Elimination Reactions
Lecture 15 - Electrophilic Addition to AlkenesLoading the player...
- 15.01 Addition of HX to Alkenes related text
- 15.02 Acid Catalyzed Polymerization of Alkenes related text
- 15.03 Epoxidation of cis-2-Butene related text
- 15.04 Epoxidation of trans-2-Butene related text
- 15.05 Bromination of Alkenes related text
- 15.06 Stereochemistry of Bromine Elimination vs. Addition
- 15.07 Electrophilic Aromatic Substitution related text
Lecture 16 - Introduction to the Carbonyl GroupLoading the player...
Lecture 17 - Alcohol Synthesis via Nucleophilic Addition to the Carbonyl GroupLoading the player...
- 17.01 Oxidation Reactions of Alcohols to Carbonyl Derivatives
- 17.02 Reduction of Aldehydes and Ketones to Alcohols with LiAlH4 and NaBH4 related text
- 17.03 Grignard Reagents - Nucleophiles for Carbonyl Addition
- 17.04 A General Synthesis of Alcohols related text
- 17.05 Synthesis of 3-Hexanol
- 17.06 Synthesis of 3-Methyl-3-Hexanol related text
- 17.07 Diastereoselective Alcohol Syntheses and the Possibility of Enantioselective Alcohol Syntheses related text
Lecture 18 - Further Nucleophilic Addition Reactions to the Carbonyl Group
Lecture 19 - Nucleophilic Substitution at the Carbonyl GroupLoading the player...
- 19.01 Carboxylic Acids - Formation and Activation related text
- 19.02 Esters - Formation related text
- 19.03 Esters - Hydrolysis and Transesterification related text
- 19.04 Reactions of Esters with Grignard and Hydride Reagents related text
- 19.05 Amides - Formation related text
- 19.06 Amides - Hydrolysis related text
- 19.07 Nitriles and their Hydrolysis to Amides and Carboxylic Acids - Tautomers related text
Lecture 20 - Consequences of Hydrogen Acidity at Carbonyl a-Carbon - Aldol and Related ReactionsLoading the player...
- 20.01 Enolate and Enol related text
- 20.02 Tau Bond Interpretation of Enolate Formation related text
- 20.03 Aldol Condensation related text
- 20.04 Aldol Condensation, Continued related text
- 20.05 Claisen (Ester) Condensation - Dieckmann Condensation related text
- 20.06 Alkylation and Decarboxylation of b-Ketoesters related text
- 20.07 Uses of the Claisen related text
- 20.08 Michael Reaction related text
- 20.09 Robinson Annulation related text
Lecture 21 - Brief Introduction to CarbohydratesLoading the player...
- 21.01 Glucaric Acid is Chiral
- 21.02 Ruff Degradation - Arabaric Acid is Chiral
- 21.03 Kiliani Synthesis - Glucose and Mannose are C-2 Epimers
- 21.04 Mannaric Acid is Chiral. Osazones
- 21.05 Emil Fischer's Solution to the Glucose Problem
- 21.06 Glucose Exists Predominantly in a Glucopyranose Ring
- 21.07 Proof of Structure of 2,3,4,6-Tetramethylglucose
- 21.08 How to Transform the Glucopyranose Structure into itsProper and Conventional Chair Conformational Rendering
- 21.09 Furanose Rings
- 21.10 Disaccharides - Lactose
- 21.11 Polysaccharides - Cellulose and Starch
Lecture 22 - Important General Subjects for ReviewLoading the player...
- 22.01 The Concept of Retrosynthetic Analysis
- 22.02 Writing Mechanisms in Organic Chemistry - The Notational Device of "Curved-Arrow Pushing"
- 22.03 A Concluding Word
Video and Related Text © 2000, 2002, 2014 Claude E. Wintner