Physics/General Programs 108b

Physics in Modern Medicine:

Applications in Imaging, Surgery and Therapy

Prof. Suzanne Amador Kane

Koshland INSC Link L103

Office Hours: TBA

Phone: (610) 896-1198, email: samador@haverford.edu

Spring 2006 Haverford College

Blackboard

Information for Instructors & Teaching Medical Physics

To reach the book website, click here

Course description (brief overview, prerequisites) Class meeting times and location
Course requirements / Information about Posters Grading/Late Policy/Honor Code/Accommodations
Syllabus (includes weekly assignments, exams, etc.) Resources

Course description

This course introduces the nonscientist to technologies important to modern medicine, and the basic physical and physiological principles which underlie them. Readings in a text prepared especially for this course, the popular scientific literature, and medical texts will treat both the scientific basis and societal implications of laparoscopic surgery, laser surgery, photodynamic therapy, ultrasound imaging, x-ray and radionuclide imaging, computer tomography (CAT or CT scans), positron emission tomography (PET scans), radiation therapy and magnetic resonance imaging (MRI). Specific medical applications discussed will include (but are not limited to): colon cancer screening, arthroscopic knee surgery, laser eye surgery, dermatological laser surgery, obstetrical ultrasound, cardiovascular ultrasound, mammography, osteoporosis screening, cancer radiation therapy, and applications of PET and MRI brain scans in neuroscience.

Enrollment Limits/Who should take this course: This course is limited to an enrollment of 40. Preference is given to students not already majoring in the natural sciences. Natural science majors may take it as an elective, although they should consult with the instructor before doing so.

Prerequisites: None. Only precalculus-level mathematics will be used.

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Textbook & Readings

The main text for the course is Introduction to Physics in Modern Medicine, by Suzanne Amador Kane, Taylor and Francis Publishers, 2003, available at the Haverford Bookstore. Reserve copies are available in White Science and Collier Libraries. Additional reserve readings can be found in the KINSC Science Library.

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Class meeting times and location

There will be three one hour lectures every week, MWF 10:30-11:30 in KINSC H108.

You are welcome to attend Physics Clinic every Wednesday and Thursday night 7-10pm in KINSC H107 (the Physics Lounge) to get help with the homework.

You are expected to attend all class meetings and you are responsible for any missed material or announcements. Absences due to athletics, interviews, etc. should be preceded by an email to the instructor to set up a makeup assignment. More than two absences for reasons other than illness per semester would be considered excessive, and may be considered in grading.

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Course Requirements

Homework assignments will be distributed roughly every two weeks in class, and due one week later at the beginning of class. See the syllabus below for more details. There will be one take-home midterm exam and a self-scheduled final exam. The homework assignments and exams will contain a combination of short quantitative problem-solving and essay-style questions. There will be one poster session as well (see details below).

Exams must be completed and turned in by the announced deadline unless special arrangements have been made in advance with the instructor, or unless you obtain a Dean's excuse.

Poster Session

There will be one poster session assigned this semester. This presentation will address the topics covered in the course from a perspective chosen by the student in cooperation with the instructor. For the poster presentation, students may work in teams of two people. For example, a student might elect to do a presentation discussing the economic consequences of laparoscopic surgery, an overview of government regulation of the medical instrumentation industry, political issues surrounding access to various medical diagnostic procedures, a discussion of social issues surrounding mammography, or safety concerns surrounding radiation. The expected level and tone is that of a journalist writing a newspaper or news magazine article, although a full bibliography and careful citation of sources is required. The poster session will be described in more detail in class.

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Grading

In determining the course grade, the following weighting will be used:

You will be able to view your relative standing and approximate grade throughout the semester.

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Late Assignment Policy

You may turn in two homework assignments up to one week late with no penalty. (Save these freebie lates for when you need them!)

Thereafter, late assignments will be graded according to the following formula:
Up to one week late: 75%
Up to two weeks late: 50%

Assignments will be graded up to one month after the due date.

Honor Code Issues

The instructor values Haverford's honor code for the integrity it fosters and the pedagogical flexibility it affords.  I expect your cooperation in respecting the following guidelines.  Please request clarification whenever necessary.

Accommodations:

Students who think they may need accommodations in this course because of the impact of a disability are encouraged to meet with the instructor privately early in the semester.  Students should also contact Rick Webb, Coordinator, Office of Disabilities Services (rwebb@haverford.edu, 610-896-1290) to verify their eligibility for reasonable accommodations as soon as possible.  Early contact will help to avoid unnecessary inconvenience and delays.

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Assignments and Course Information On-line

All assignment solutions and lecture Powerpoint presentations will be posted online on the TRIPOD Blackboard system (click here to enter).

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Syllabus (approximate)

Week of Topic Assignments Exams & Due Dates
16 Jan Intro; Optics: Endoscopic and laparoscopic surgery

HW1 Due Fri. Jan 27

Chapter 2: Questions 1 & 2; Problems 2.1, 2.4, 2.5, 2.6, 2.7

 
23 Jan

Endoscopy continued; Videos; Virtual Surgery, Telemedicine

 

HW1 Due Fri. Jan 27
30 Jan Laser Surgery--applications in ophthalmology, dermatology, general surgery, photodynamic therapy

HW2 due Fri Feb 10

Chapter 3: Questions 3.2, 3.4

Problems 3.1, 3.2, 3.3, 3.5

 
6 Feb Laser Surgery continued

 

HW2 due Fri Feb 10
13 Feb Ultrasound Imaging--applications in obstetrics and cardiology

Topic of Poster Session (plus short bibliography & choice of partner) Due Friday Feb. 24

HW3 due Fri March 3--note you have three weeks for this problem set

Chapter 4:

Problems 4.2, 4.4,4.6 (also for Problem 4.6, make a sketch of the approximate echo intensity vs. time plot you would expect, similar to that shown in Figure 4.9(a) on page 105);. 4.8, 4.10, 4.12, 4.13

 
20 Feb Ultrasound continued--applications in obstetrics and cardiology

 

Due Friday Feb. 24: Topic of Poster Session (and your choice of partner) , plus a short bibliography of sources (5 + sources with full citations)
27 Feb

X-ray imaging--applications in mammography, osteoporosis screening

 

 

HW3 due Fri March 3
6 Mar SPRING BREAK SPRING BREAK SPRING BREAK
13 Mar

X-ray imaging.continued--applications: Computer Tomography (CT scans)

 

HW4 due Fri March 31

Chapter 5: Question 5.6

Problems 5.3, 5.5, 5.8, 5.11, + epidemiology problem (see Blackboard)

Take-home Midterm out Fri 17 March; due beginning of class Mon Mar 20--Covers Chapters 2,3,4, other topics covered in lecture

20 Mar Nuclear Medicine: radionuclide imaging, bone scans; PET imaging, nuclear medicine imaging of the brain

 

HW4 due Fri March 24
27 Mar Nuclear Medicine continued

HW5 due Fri. April 28 (extended deadline) at 5pm in my office

Homework #5

Chapter 6: Problems 6.4, 6.6 (Note for problem 6.6 that the lecture from Week 11 (lecture 1 & 2) have a discussion of how to use logarithms to do problems like this, in addition to the book’s discussion of logarithms.)
Chapter 7: Question 7.2 & 7.3, Problem 7.1
Chapter 8: Question 8.6, Problem 8.2

 
3 April Radiation medicine and safety: cancer radiation therapy

 

 
10 April Radiation medicine and safety continued.; cancer radiation therapy

 

 
17 April Magnetic Resonance Imaging (MRI)

Poster session during class time on Monday and Tuesday of this week

 

 
24 April

MRI Contd: applications in sports medicine, breast imaging, brain imaging

 

 

 

Last day of classes--all work except for Final Exams due by 5pm Friday 28 April

Finals Period Self-scheduled Final Finals Final Exam--emphasis on material since the midterm

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Resources

List of Possible Poster Topics

The Internet is a valuable and up-to-date resource for information about medical physics, and we will make extensive use of it throughout the semester. This section will contain listings of relevant internet resources for each section of the course. The following were chosen more for their interest to general audiences than for completeness. Let your instructor know of interesting and useful sites you find on your own!

FDA Center for Devices and Radiological Health is a good starting place for examining issues relating to medical device safety and regulation.

Bioethics.net An online journal of resources on bioethics

Physlets for using with Medical physics: http://science.uniserve.edu.au/school/curric/stage6/phys/physapplets.html#9.6

"Modern Medical Miracles" Kansas State Website on Medical Imaging, with various resources

Laparoscopy on-line resources

1ST STOP Laparoscopy.com This very interesting and detailed site explains some specifics about laparoscopic surgery of various types, and includes case studies, movies and images drawn from a variety of areas.

Atlas of Gastrointestinal Endoscopy

Fiberoptic Biosensors being developed in the lab of Dr. David R. Walt at Tufts University; check out commercial applications at Illumina Corp.

An interview with physician Col. R.M. Satava, MD. about telemedicine and its applications in the military and civilian medicine.

CRASAR (Center for Robot-Assisted Search and Rescue)--read about how telemedicine and robotics are helping save lives in natural disasters and the aftermaths of terrorist attacks

CNN News report Read about the remarkable Video Pill here and see movies taken inside the body.

Laser Surgery

Beckman Institute: a prominent research institution which also offers various dermatological laser surgery procedures

Laser Eye Surgery site on LASIK and other techniques

Explanations of Refractive Errors using helpful animations explaining how LASIK and other refractive eye surgery works

Ultrasound Imaging

1ST STOP Obstetrical Ultrasound website by Dr. Joe Woo

Should Ultrasound Imaging go commercial? Companies like Fetalfotos.com are marketing fetal imaging.

X-ray imaging

Check out these websites for a discussion of how x-ray imaging and Computed Tomography (CT) scanning work: Physics 2000: Einstein's Legacy

Nuclear Medicine

1ST STOP Let's Play PET

Radiation Therapy

Magnetic Resonance Imaging

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This page maintained by Suzanne Amador Kane, samador@haverford.edu, Last updated 1/06/2006