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Haverford College

Marian E. Koshland Integrated Natural Sciences Center

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Biography of an Experiment

429px-GyorgyiNIHScience is to see what everyone else has seen but think what no one else has thought. — Albert Szent-Györgyi

The Biography of Experiment Series is an ongoing cooperative effort between students and faculty at Haverford College to expose undergraduates to the stories behind influential manuscripts in the Natural Sciences.

Posted on this site are excerpts of original manuscripts, each of which has been annotated by undergraduates who have spent a semester critically evaluating the work and assessing the authors’ own perspectives.

By including their interviews with primary investigators, links to background information, and tips for understanding and critically interpreting data, these undergraduates have developed a unique pedagogical tool that should enhance their peers ability to navigate and understand the primary literature. Developing scholars will benefit from their colleagues’ insights as they are invited to explore the living history of a scientific inquiry.

Article Title Students
Injection of the cAMP-responsive element into the nucleus of Aplysia sensory neurons blocks long-term facilitation (Dr. Eric R. Kandel, with Pramod K. Dash and Binyamin Hochner, 1990)

Sara Berman '10 and Jill Geratowski '11

The Invention of the Dye-sensitized Solar Cell (Michael Graetzel and Brian O'Regan's 1991)

Alex Vargo and Jacob Olshansky

Effect of neonatal handling on age-related impairments associated with the hippocampus (Michael J. Meaney, David H. Aitken, Chayann Van Berkel, Seema Bhatnagar, Robert M. Sapolsky, 1990)

David Fischer '10 and Michele Buonora '11

The Search for a Predtor of CD4 Cell Count Continues: Total Lymphocyte Count is Not a Substitute for CD4 Cell Count in the Management of HIV-Infected in a Resource-Limited Setting

Amy Labar '10

Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells (Hazuda et al, 2000)

Nina Salinger '07

Major Biology, Minor Chemistry

Identifying the start site for protein translation (Steitz and Jakes, 1975)

Emily Hinchcliff and Taylor Sundby

Biology Majors '08

Mutational analysis of the start site for protein translation (Jacob, Dahlberg and Santer

Taylor Sundby and Emily Hinchcliff

Biology Majors '08

AIRE and autoimmunity (Diane Mathis/Christophe Benoist, 2001) Christen Fornadel,
Biology Major '04
Sorting of Protein A to the Staphylococcal Cell Wall Olaf Schneewind, Peter Model, and Vincent A. Fischetti, 1992 Faith Wallace-Gadsden,
Biology Major '05
Protein folding and amyloidosis (Christopher Dobson/Mark Pepys, 1997) Katie Hart,
Biology Major '04
On the Psychology of Prediction (Daniel Kahneman and Amos Tversky), 1973

Andrew Armstrong, '05

The melanocortin-1 receptor gene mediates female-specific mechanisms of analgesia in mice and humans. Susannah Locke,
Biology Major with a Minor in Psychology, '05