Bio200

Cell Structure and Function

Quarter 1

Fundamentals of Cell Biology

 

Jenni Punt

jpunt@haverford.edu

S308-S309

 

Office Hours: M 4pm, WF 10:30am

Objectives, Requirements, and Resources

Syllabus (more on Blackboard)

 

Date

Topic

Readings

Laboratory

Fundamental Biological Theories

Week 1

Aug 31, Sept 2

Evolution

http://evolution.berkeley.edu/

http://www.edge.org/3rd_culture/mayr/mayr_print.html

The tree of life and the three domains

http://www.ucmp.berkeley.edu/alllife/threedomains.html

ppt.

The Origin

Introduction

 

Cooper

Ch1 (3-8)

From organism to cell: dissection (optional)

Week 2

Sept 7,9

 

DNA and the Central Dogma

http://web.mit.edu/esgbio/www/dogma/dogmadir.html

http://www.exploratorium.edu/origins/coldspring/printit.html

ppt.

Cooper

Ch3 (89-103)

Figs 3.4-3.13

Historical Experiment: The molecular basis of inheritance

 

Sept 10 Problem Set #1 Due

Week 3

Sept 14,16

Cell Theory

http://www.ucmp.berkeley.edu/history/leeuwenhoek.html

The theory of endosymbiosis

http://evolution.berkeley.edu/

ppt.

Cooper

Ch1 (8-15)

 

Ch10 (399-403, 415-18, 26) Figs 1, 3, 13, 24

Historical Experiment, cont.

Sept 21 In-class exam

Fundamentals of Cell Structure and Function

Week 4

Sept 23

Topic: Membranes

Case study: Cholera – Why is sugar water a cure?

http://www.jci.org/cgi/content/full/113/3/334#B27

http://www.textbookofbacteriology.net/

 

Cooper

Ch 12 (483-93)

Figs1-13, 22, 30-33

 

Original experiment: Antibiotics and bacterial growth

 

1. The growth curve

Week 5

Sept 28, 30

Topic: Organelles – Endomembrane network

Case study: Albinism and the immune system – what is the connection?

http://www.textbookofbacteriology.net/

 

Cooper

Ch8 (323-35) Figs 1-10

Ch9 (355-366, 382-389) Figs 1-10, 21-24, 32-36

2. The influence of antibiotics on cell growth

Article on Antibiotic Resistance

Week 6

Oct 5,7

Topic: Cytoskeleton

Case study:  Botox – How does it work?

http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/M/Muscles.html

http://www.textbookofbacteriology.net/

Cooper

Ch11

3. Confirmation of hypothesis

Oct 6 Problem Set #2 Due

Week 7

Oct 19, 21

Topic: Cell cycle

Case study: Cancer – what do viruses have to do with it?

http://www.nobel.se/medicine/laureates/2001/hartwell-lecture.html

http://www.nobel.se/medicine/laureates/1989/varmus-lecture.html

Cooper

Ch 14 (591-615)

Figs 1-31

Ch 15 (648-649)

4. Discussion of data

Oct 21, Take-home exam passed out  DUE Oct 29, 5:30pm