Bio308

Immunology (Overview)

Haverford College

 

Jenni Punt

jpunt@haverford.edu

S308-S309

 

Office Hours: by e-mail (afternoons are best)

 

Syllabus (more on Blackboard)

 

Date

Topic

Readings

Assignments

Week 1

Oct

 25, 27, 29

Overview of the immune system

Introduction to the innate immune system

Adopt a pathogen

Janeway

Ch. 1, 2

Essay  #1: DUE November 1

Pathogenicity of selected infectious agent

Week 2

Nov

1,3,5

Introduction to the acquired immune system – key concepts

B cell – antigen recognition

T cell – antigen recognition and the concept of MHC restriction

 

Janeway

Ch. 3, 4

Quiz #1:  November 5 in-class

 

Week 3

Nov

8,10,12

Generation of diversity – in-class review (Jenni is not there)

VDJ recombination – Guest lecturer (Dave Allman, U. Penn)

T cell/APC interaction and the connections between the innate and adaptive immune system

Janeway

Ch. 4, 5

Essay #2: DUE November 15

How does the innate immune system manage your pathogen?

Week 4

Nov

15,17,19

Receptor signaling

Janeway

Ch. 6

Quiz #2: November 19 in-class

Nov. 19: Class discussion of pdf selection for annotated pdf final project

Week 5

Nov

22,24

The adaptive immune system in more detail – effector cells

Janeway

Ch. 8, 9, 10

Essay #3: DUE Dec. 1

How does the acquired immune system manage your pathogen?

Week 6

Nov 29

Dec 1, 3

Lymphocyte development and selection

Janeway

Ch.7

Quiz #3: December 3 in-class

Dec. 3: Class discussion of manuscript selection

Week 7

Dec

6, 8, 10

How pathogens dodge the immune system

Janeway

Ch. 10, 11

Essay #4: DUE Dec. 10

How does your pathogen dodge the immune system?

Annotated pdf due at end of exam period