Drosophila (male)

Drosophila (female)
A Faculty Development Course
Computer Applications in the Biosciences


C. elegans






In the article "Informatics moves to the head of the class", which appears in the June issue of Bio-IT World and in its online version at http://www.bio-itworld.com/archive/061202/class.html (free registration needed to view text), Dr. Philip Meneely of Haverford College's Biology Department and Dr. Warren Ewens of University of Pennsylvania's Biology Department were interviewed.

Suzanne Amador Kane of Haverford College's Physics Department presented a talk May 16, 2002 at Bryn Mawr's Math/Science Teaching Symposium. The title of her talk was "Bioinformatics: A HHMI Faculty Development Course in Computer Applications in the Biosciences and its Curricular Consequences".

Haverford College is fortunate to have been the recipient of a grant from the Howard Hughes Medical Institute to fund a development program for the faculty. The topic for the Fall 2001 semester was Bioinformatics.

Bioinformatics is the science of developing computer databases and algorithms for the purpose of speeding up and enhancing biological research. Bioinformatics is being used most noticeably in the Human Genome Project, the effort to identify the 35,000 genes in human DNA. New academic programs are training students in Bioinformatics by providing them with backgrounds in molecular biology and in computer science, including database design and analytical approaches.

The format of the course consisted of a Tuesday afternoon seminar for eleven weeks. Beginning October 9 the afternoon lectures were followed by hands-on workshops*. The afternoon seminars were open to the general public, while the evening workshops were limited to the seven enrolled faculty (the same seven people each week). The enrolled faculty came from Biology, Chemistry, Physics, Mathematics and Computer Science. Expertise varied, which enhanced the opportunity to teach each other. The enrolled faculty continue to meet to develop course modules, research projects, and so on.

*The evening workshops are reserved for enrolled faculty.

Lecture Schedule Fall 2001
Times and dates are subject to change based upon faculty & course leader consensus.
Location of lectures are in Sharpless Auditorium
and workshops will be held in Stokes 8.


4:30 - 6:00pm
Sharpless Auditorium

Stokes 8
Tues. Sept. 11
Introduction Warren Ewens, Greg Grant &
Elisabetta Manduchi
Tues. Sept. 18 Alignments
dynamic programming
Elisabetta Manduchi
Tues. Sept. 25 Substitution Matrices Warren Ewens
Tues. Oct. 2 Multiple alignments
Gibbs sampling and HMM's
Greg Grant
Tues. Oct. 9 BLAST Warren Ewens &
Jessica Kissinger (guest lecturer)
Fall Break
Tues. Oct. 23 Databases Jonathan Crabtree (guest lecturer)


Tues. Oct. 30 Gene finding Greg Grant Workshop
Tues. Nov. 6 Gene expression I Elisabetta Manduchi
Tues. Nov. 13 Gene expression II Elisabetta Manduchi Workshop
Tues. Nov. 20 Phylogeny Greg Grant Workshop
Tues. Nov. 27 Protein Folding - A Conserved Domain Database Stephen Bryant (Distinguished Visitor) Workshop
*Workshops are reserved for enrolled faculty only.



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Course Leaders & Guest Lecturers

We are very fortunate to have Greg Grant, Elisabetta Manduchi & Warren Ewens of
University of Pennsylvania Center for Bioinformatics leading this course. They currently teach a Bioinformatics course at University of Pennsylvania and are excited about their innovative tag-team approach to teaching this faculty development course.

In addition, the following guest lecturers will be offering their expertise:
- Jonathan Crabtree of University of Pennsylvania's Engineering & Applied Science
- Jessica Carol Kissinger of the University of Pennsylvania

- Stephen Bryant of the National Center for Biotechnology Information (NCBI)

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Last update September 30, 2003