Courses: Molecular Motors and Biological Nano-Machines (BIOLH351D01)
The world of the cell contains a rich array of molecular machinery that carries out life's dynamic processes. Interdisciplinary studies of these mechanisms employing a variety of biological, chemical and physical approaches are revealing a wealth of detail spanning from visible phenomenon to the scale of atoms and molecules. Extensive reading of the primary literature will be used as a basis for student-led discussions. Topics will be selected from a list including viral assembly, cellular clocks, mechanoenzyme engines, biosynthetic machinery and the assembly and regulation of cytoskeletal arrays. These systems provide novel insights into how work is accomplished (and regulated) in a nano-scale environment and serve as models for the development of microtechnologies for science and medicine. Enrollment limited to 15 students.
Prerequisites: Biology 302 or consent of instructor.
Fulfills: NA II
Haverford, Shrp 213