Courses: Apoptosis: A Matter of Life and Death (BIOLH353E01)
Cell death is as important to an organism as cell differentiation and proliferation. In order to shape organs, limbs, and digits, form neural pathways, build a useful repertoire of specificities in the immune system, and start and stop inflammatory reactions, an organism needs to be able to regulate cell death via a highly regulated process we call apoptosis. A lack of regulation between cell death and proliferation underlies many disease states, including cancer and AIDS. In this course we will explore current advances in our understanding of the molecular basis for cell death (apoptosis), its regulation, its relationship to cell differentiation and proliferation, and its role in disease processes. The material will be presented in seminar format where primary literature will be read extensively and students will take the lead in the discussion and debate of current controversies.
Prerequisites: Biology 200 and one semester of 300 level Biology or consent of instructor.
Fulfills: NA II
Haverford, Kosh E309